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tetrahydromethanopterin biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene_5''-phosphate + reduced_acceptor <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol_5''-phosphate + acceptor not assigned

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-alpha_-D-_ribofuranosyl_triphosphate]-D-ribitol + (S)-2-hydroxyglutarate <=> 7,8-dihydromethanopterin + diphosphate not assigned

7,8-dihydroneopterin <=> glycolaldehyde + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 4.1.2.25 dihydroneopterin aldolase

4-hydroxybenzoate + 5-phospho-alpha-D-ribose_1-diphosphate + H+ <=> 4-(beta-D-ribofuranosyl)hydroxybenzene_5''-phosphate + CO2 + diphosphate 2.4.2.54 beta-ribofuranosylphenol 5'-phosphate synthase

5,6,7,8-tetrahydromethanopterin + acceptor <=> 7,8-dihydromethanopterin + reduced_acceptor 1.5.99.15 dihydromethanopterin reductase (acceptor)

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-alpha_-D-_ribofuranosyl_5-phosphate]-D-ribitol + ATP <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-alpha_-D-_ribofuranosyl_triphosphate]-D-ribitol + AMP not assigned

4-(beta-D-ribofuranosyl)-N-succinylaminobenzene_5''-phosphate <=> 4-(beta-D-ribofuranosyl)aminobenzene-5''-phosphate + fumarate 4.3.2

4-(beta-D-ribofuranosyl)aminobenzene-5''-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl_diphosphate <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene_5''-phosphate + diphosphate 2.5.1.105 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase

S-adenosyl-L-methionine + 5,10-methylenetetrahydromethanopterin + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + [4Fe-4S]+1_iron-sulfur_cluster + reduced_acceptor <=> 2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin + 5''-deoxyadenosine + L-methionine + 7,8-dihydromethanopterin + [4Fe-4S]2+ + acceptor 2.1.1

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol + 5-phospho-alpha-D-ribose_1-diphosphate <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-alpha_-D-_ribofuranosyl_5-phosphate]-D-ribitol + diphosphate 2.4.2

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin + ATP <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl_diphosphate + AMP + H+ 2.7.6.3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase

4-(beta-D-ribofuranosyl)hydroxybenzene_5''-phosphate + L-aspartate + ATP <=> 4-(beta-D-ribofuranosyl)-N-succinylaminobenzene_5''-phosphate + ADP + phosphate + H+ 6.3.1

chorismate <=> 4-hydroxybenzoate + pyruvate 4.1.3.40 chorismate lyase

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol_5''-phosphate + H2O <=> [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol + phosphate 3.1.3

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